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Fever Isn’t Cooking Germs—It Supercharge Immunity
bbotplayer1Why does a fever help you recover from infection? In this video, I explained why fevers don’t “cook” germs but instead power up your immune army — from neutrophils and T cells to heat shock proteins that speed cell trafficking and antigen delivery. Learn how modest temperature boosts protect cellular machinery, enhance pathogen recognition, and why animals across 600 million years of evolution turn up the heat when infected. Perfect for sci-curious adults interested in immunology, physiology, and evolutionary biology. If you enjoyed this deep dive, please like and share the video to help others discover it. #fever #immunology #HeatShockProteins #scienceexplained REFERENCES ************** Appenheimer, M.M. & Evans, S.S. (2018) Temperature and adaptive immunity. Handbook of Clinical Neurology 156: 397–415. https://www.sciencedirect.com/science/chapter/handbook/abs/pii/B9780444639127000242?via%3Dihub Casadevall, A. (2016) Thermal Restriction as an Antimicrobial Function of Fever. PLoS Pathog 12(5): e1005577. https://journals.plos.org/plospathogens/article?id=10.1371%2Fjournal.ppat.1005577 ChangDong L. et al. (2019). Fever Promotes T Lymphocyte Trafficking via a Thermal Sensory Pathway Involving Heat Shock Protein 90 and α4 Integrins. Immunity 50(1):137-151. https://www.cell.com/immunity/fulltext/S1074-7613(18)30495-3 Evans, S.S. et al. (2015) Fever and the thermal regulation of immunity: the immune system feels the heat. Nature Reviews Immunology 15(6): 335+. https://pmc.ncbi.nlm.nih.gov/articles/PMC4786079/ Hasday, J.D., Thompson, C., Singh, I.S. (2014) Fever, immunity, and molecular adaptations. Comprehensive Physiology 4:109–48. https://onlinelibrary.wiley.com/doi/10.1002/j.2040-4603.2014.tb00544.x Hasday, J.D. & Singh, I.S. (2000) Fever and the heat shock response: distinct, partially overlapping processes. Cell Stress Chaperones 5:471–480. https://pmc.ncbi.nlm.nih.gov/articles/PMC312879/ Javid, B., MacAry, P.A. & Lehner, P.J. (2007) Structure and function: heat shock proteins and adaptive immunity. Journal of Immunology 179:2035–2040. https://academic.oup.com/jimmunol Mackowiak, P. A.: Direct effects of hyperthermia on pathogenic microorganisms: teleological implications with regard to fever. Reviews of Infectious Diseases 1981, 3: 508–518. https://academic.oup.com/cid/article-abstract/3/3/508/307776 CHAPTERS ▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀▀ 0:00 Fever's Hidden Helpers 0:23 The Heat of Life 1:58 Dangers of too much heat 3:00 Should You Fight Fever?22 views 2 comments -
The Secret Ingredient That Keeps Food Fresh for 1 Year
bbotplayer1Welcome — in this video I explain why food spoils, why it develops a bad smell, and what manufacturers use to extend shelf life (including a plain-language look at sodium benzoate). If you want less waste and safer homemade chutney, sauces, juices or ice-cream, watch till the end. Chapters: 00:00 Introduction: Why Does Food Go Bad? 00:24 The Three Main Causes of Food Spoilage 00:36 Role of Microorganisms: Bacteria and Fungi 01:04 The Science of Smell: Volatile Compounds Explained 02:11 Spoilage in Specific Foods: Chutneys, Juices, and Ice Cream 02:32 How Manufacturers Prevent Spoilage 02:51 Meet the Secret Ingredient: Sodium Benzoate (E211) 03:49 Safety and Side Effects: How the Body Processes It 04:16 Common Uses: Ketchup, Jams, and Personal Care Products 04:31 Usage Guide: Proper Ratios for Preservation 05:30 Where to Buy and Final Tips114 views 2 comments -
This AI Designed a Drug in 18 Months
bbotplayer1Artificial Intelligence is transforming the future of medicine. In this video, we explore how AI is discovering new drugs faster, cheaper, and more accurately than traditional methods. We also look at a real example — INS018_055, one of the world’s first AI-designed drugs, created for Idiopathic Pulmonary Fibrosis (IPF). Learn how AI searches millions of molecules, predicts success rates, and designs brand-new treatments.175 views 1 comment -
The Digestive System
bbotplayer1Discover how your body turns food into energy! In this video, we take you inside the human digestive system — from the moment food enters your mouth until it becomes nutrients your body uses. Learn how each organ — mouth, esophagus, stomach, liver, pancreas, small intestine, and large intestine — plays a vital role in digestion.104 views 2 comments -
Who Discovered Fire? — The Story of the First Hearths
bbotplayer1A cinematic deep-dive into how early hominins learned to control fire — from lightning-lit wildfires to the first hearths that changed diet, technology, and society. Discover the archaeological evidence and why this single skill reshaped human history.49 views 1 comment -
What Extreme Dieting Actually Does To Your Body
bbotplayer1Are you losing weight — but damaging your health? This research-backed explainer shows the hidden risks of rapid or extreme dieting and gives evidence-based steps to lose fat safely while protecting muscle and health. Losing excess weight can improve blood sugar, blood pressure and mobility — but the way you lose matters. Rapid, repeated, or poorly planned weight loss can cause metabolic slow-down, muscle loss, gallstones, electrolyte problems and increased risk of disordered eating. This video explains the science behind those risks and offers 6 evidence-based steps to preserve your health while you lose weight. Sources / further reading: Guidance and reviews from PubMed / NCBI reviews on adaptive thermogenesis, weight cycling, muscle preservation during weight loss, gallstones linked to rapid loss, and refeeding syndrome; clinical guidance from National Heart, Lung, and Blood Institute (NHLBI), StatPearls, Harvard Health, and reputable clinical resources. #Dieting #WeightLoss #Health59 views 1 comment -
Navigate the Night- Stars as Your Guide 2025-05-20
bbotplayer1stars constellations directions finding way in jungle and desert45 views 3 comments -
Unlock the Night Sky- Spot Polaris, Orion, constellation
bbotplayer1Unlock the Night Sky- Spot Polaris, Orion, constellation48 views 1 comment -
Survive a Snake Bite- Essential Steps
bbotplayer1Survival, snake bite, emergency58 views 2 comments -
Survive Drowning: Life-Saving Water Rescue Techniques
bbotplayer1Struggling in open water? Don’t let panic take over—master these 5 simple, proven techniques to stay afloat, signal for help, and buy yourself life-saving time. Whether you’re caught in a pool, lake, or open sea, this step-by-step guide will teach you how to: Tilt & Breathe – Release tension and establish a calm breathing rhythm Flutter Kick – Use small, efficient kicks to conserve energy Hand Scull – Stabilize yourself with underwater “Y”-shaped strokes Float on Your Back – Rest safely while you recover Signal for Rescue – Wave, shout, and make yourself visible35 views 1 comment