What Is an Electron Microscope & How Does It Work?

The electron microscope (EM) is a tool for capturing high-resolution images of biological and non-biological material. It’s used in biomedical research to look into the structure of tissues, cells, organelles, and macromolecular complexes in great detail. The employment of electrons (which have very short wavelengths) as the source of illuminating light leads to the great resolution of em pictures. To address specific issues, electron microscopy is employed in concert with several ancillary techniques (e.g., thin sectioning, immuno-labeling, negative staining). Em pictures reveal important details on the structural basis of cell function and illness.

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