Glucuronic acid level as biomarker of longevity and healthspan

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Glucuronic acid
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Glucuronic acid is an organic compound that belongs to a class of molecules called carboxylic acids. It is found in the body and helps the liver remove toxic substances from it. Glucuronic acid can be synthesized by humans through a process called glucuronidation, which occurs when certain enzymes react with alcohols or phenols.

Glucuronic acid is an important part of the human body because it helps to remove toxins from the body. Glucuronic acid can also be used to help with kidney stones and gout.

Glucuronic acid is also used in the synthesis of glycosaminoglycans, which are important for cartilage and bone formation.

A study on humans and mice has reported that circulating glucuronic acid is a robust biomarker of mortality that is conserved across species.

It has been found that glucuronic acid levels are significant predictors of all-cause mortality in three population-based cohorts from different countries, as well as in a longitudinal study of genetically heterogenous mice.

Additionally, it has been found that glucuronic acid levels increase with age and predict future healthspan-related outcomes.

Elevated serum levels of glucuronic acid have been reported in human studies of diabetes, hepatocellular carcinoma, hepatitis, cirrhosis, and obstructive jaundice.

All together, these results seem to demonstrate that glucuronic acid could be a robust biomarker of longevity and healthspan.

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Topic related to: LONGEVITY, HEALTH, IMMUNITY, INFLAMMATION, ANTIAGING, LIFESPAN, Mitochondria, HEALING, SUPPLEMENTS, HEALTHY LIFE, IMMUNE SYSTEM, LONGEVITY PROTOCOL.

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