Rosmarinic acid

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Rosmarinic acid
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Rosmarinic acid is an ester of caffeic acid that is found in rosemary and in some fern and hornwort species. Rosmarinic acid has been demonstrated to have health promoting effects through its anti inflammatory, anti diabetic, antiviral, anti oxidant and antibacterial properties. Rosmarinic acid exerts its anti-inflammatory disease through many mechanisms. It has been shown to modulate nuclear factor NF kappa B pathway. Nuclear factor NF kappa B pathway has been considered a major target for anti-inflammatory drugs for being a prototypical proinflammatory signaling pathway. NF kappa B activation leads to the activation of various pro-inflammatory genes, including cytokines and chemokines, thereby regulating inflammation. In human inflammatory diseases, NF kappa B activation is involved with rheumatoid arthritis, atherosclerosis, asthma, and inflammatory bowel disease. In asthma, rosmarinic acid has been shown to inhibit the activation of NF kappa B leading to the reduction of inflammatory cells and excessive mucus secretion in the airways.
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Topic related to: LONGEVITY, HEALTH, IMMUNITY, INFLAMMATION, ANTIAGING, LIFESPAN, Mitochondria, HEALING, SUPPLEMENTS, HEALTHY LIFE, IMMUNE SYSTEM, LONGEVITY PROTOCOL.

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