Beta-hydroxybutyrate and Alzheimer's disease

More and more people are improving their health and getting biologically younger this year with the help of the best professionals | Work with a health coach on a monthly basis, and start improving your health from tomorrow. [email protected] Services of our professionals: health and longevity consultations, health and longevity research for private and business clients, helping you create a personalized protocol for your needs.
New email for contact: [email protected] Beta-hydroxybutyrate is one of the most abundant ketone bodies in blood circulation. It is synthesized and released by the liver from fatty acids and acts as a source of energy, when the amount of glucose in the blood is too low to support the body's energetic needs during periods of prolonged exercise, fasting, or absence of dietary carbohydrates. Recent research have been discovering other various benefits of beta-hydroxybutyrate, especially in aging-related diseases like Alzheimer's disease. According to an article published in the Journal of Neuroinflammation, BHB has been found to attenuate Alzheimer's disease pathology by inhibiting NLRP3 inflammasome activation. In the study, mice treated with B H B had fewer amyloid plaques and less pronounced microgliosis compared to untreated control mice. Amyloid plaques and microgliosis are both characteristics of Alzheimer's disease. The accumulation of amyloid plaques between neurons causes them to die and induce inflammation around that area, which further reinforce the death of neurons. Microgliasis is the proliferation of activated microglia at the site of inflammation to protect neurons from neurotoxic plaque, but also promotes neuroinflammation that leads to neuronal damages and death. NLRP3 activation through dietary BHB or fasting that promotes the natural production of BHB could be an effective therapeutic strategy for Alzheimer's disease.
We would like to hear about your own experience with this topic. Leave a comment. If you have any friends who may find this information helpful or interesting, you can use the share button and share this video with them on Facebook, Twitter, WhatsApp, or any other social media. Lastly, remember that it is important to talk to your doctor or other professional before beginning any sort of supplementation or treatments. Feel free to contact us if you want us to give you the contact information of professionals who work with our network.
***
Topic related to: LONGEVITY, HEALTH, IMMUNITY, INFLAMMATION, ANTIAGING, LIFESPAN, Mitochondria, HEALING, SUPPLEMENTS, HEALTHY LIFE, IMMUNE SYSTEM, LONGEVITY PROTOCOL.

Contact: [email protected]