Centrophenoxine

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Centrophenoxine
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Centrophenoxine is a cholinergic nootropic developed in France in 1959. Centrophenoxine is usually considered an ageing reversal drug in the cholinergic system. It is a combination of dimethylethanolamine or DMAE and parachlorphenoxyacetic acid or pCPA. DMAE is the effective part of centrophenoxine. It is a precursor of acetylcholine and helps increase acetylcholine levels in the brain, which is decreased in both concentration and function in patients with Alzheimer's disease. Acetylcholine is a neurotransmitter that is essential in processing memory and learning. Aside from increasing acetylcholine levels in the brain, DMAE is also an antioxidant. It has been reported to directly react with hydroxyl, ascorbyl, and lipid radicals, which are one of the primary culprits in neuron degeneration and death. Centrophenoxine also decreases lipofuscin in the brain, which is one of the most consistent features of aging. Lipofuscin aggregates in the brain are morphologic changes in different cells in the body, especially in certain areas of the brain, liver, kidneys, heart, and adrenals. Most of the lipofuscin aggregates prevent the degradation of oxidized proteins and increase the formation of free radicals, which contribute to aging-related pathologies.
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Topic related to: LONGEVITY, HEALTH, IMMUNITY, INFLAMMATION, ANTIAGING, LIFESPAN, Mitochondria, HEALING, SUPPLEMENTS, HEALTHY LIFE, IMMUNE SYSTEM, LONGEVITY PROTOCOL.

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