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L-carnitine
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L-carnitine
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L-carnitine is an amino acid that is naturally present in almost all cells of the body. L-carnitine is also found in several food sources especially red meats such as beef and lamb. L-carnitine is known as a molecule plays a vital role in energy metabolism and in the metabolism of lipids. Recent studies have reported that this amino acid can be applied in various clinical therapies. L-carnitine has been proposed as a supplement that can reduce frailty status and improve cognitive function among prefrail older adults. Frailty is a clinical condition of older individuals characterized by age associated declines that makes them more vulnerable to endogenous and exogenous stressors. In a study, the efficacy of 10 week L-carnitine supplementation on frailty status and its biomarkers and also physical function, cognition, and nutritional status among prefrail older adults in Klang Valley has been tested. The results of the study has demonstrated that mean scores of frailty index score and hand grip test were significatly improved in subjects supplemented with L carnitine. Moreover, L-carnitine supplementation has been shown to be beneficial in improving physical, mental, and cognitive function. This positive outcome of L carnitine supplementation against frailty and aging related pathologies could be associated with what was reported in a study by Crenstil in which it was stated that L-carnitine deficiency is related to pathophysiolical changes in frailty, such as neuromuscular abnormalities, inflammation, decrease energy production, and immune impairment.
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Topic related to: LONGEVITY, HEALTH, IMMUNITY, INFLAMMATION, ANTIAGING, LIFESPAN, Mitochondria, HEALING, SUPPLEMENTS, HEALTHY LIFE, IMMUNE SYSTEM, LONGEVITY PROTOCOL.
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