Bromelain

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Bromelain is a group of proteolytic enzymes derived from the fruit and stem of pineapple. Bromelain contains different active ingredients including phosphatases, glucosidases, peroxidases, cellulases, glycoproteins, and carbohydrates. Bromelain is promoted as dietary supplement for alleviating swelling and pain due to its anti-inflammatory activity especially for sinusitis and osteoarthritis. A clinical study has reported that bromelain reduced pain and inflammation to 103 patients with osteoarthritis of the knee after 6 weeks of oral administration. Bromelain has been recommended as an adjuvant in the treatment of chronic and inflammatory autoimmune diseases. Bromelain is also combined with quercetin, a flavonoid widely used for its antibacterial and antiviral properties characterized by its ability to stimulate the immune system but isn't well-absorbed by the body. Taking these supplements together maximizes their effect on boosting up the immune system that can help related conditions. Beside anti-inflammatory effect, bromelain is also promoted to manage and treat thrombosis, as well as in the management of heart disease, due to its ability to prevent the formation of blood clot by inhibiting the synthesis of fibrin, a protein involved in blood clotting. In rats, high concentration of bromelain leads to significantly longer prothrombin time and activated partial thromboplastin time. Recently, studies have demonstrated the anti-cancerous activity of bromelain. Most of the in vitro and in vivo studies on mouse and human cells have demonstrated that Bromelain has the ability to promote apoptotic cell death on cancer cells through various mechanisms. In one study bromelain has increased the expression of p53 and Bax in mouse skin, the well-known activators of apoptosis. It's important to talk to your doctor or other professional before beginning any sort of supplementation or treatments. Feel free to contact us if you want us to give you the contact information of professionals who work with our network.