Scurvy (Vitamin C Deficiency) - Causes, Signs & Symptoms, Diagnosis & Treatment

Scurvy is a state of dietary deficiency of vitamin C, also known as ascorbic acid. Humans lack the ability to synthesize vitamin C within the body. Therefore, they depend on exogenous dietary sources to fulfill their vitamin C requirements. Although scurvy is uncommon, it still occurs and can affects children and adults who have chronic vitamin C deficiency. The total body pool of vitamin C is around 1500 mg, with higher concentrations found in glandular tissue, and lowest in muscle & fat tissue. Vitamin C is metabolized by the liver via glucuronidation and sulphation. Excess amounts in the body are excreted unchanged by the kidneys.
Scurvy occurs when vitamin C has been eliminated from the diet for at least 3 months and when the body pool of vitamin C falls below 350 mg.

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