SARS-CoV-2 T-cell infection and HIV similarity - COVID-19 vaccines update 46

A new discovery that the SARS-CoV-2 virus can infect T-cells via LFA-1 protein which is also how HIV can infect T-cells. We also discuss the fact that the spike protein has been known to contain fragments also found in HIV proteins. However, it is not the spike protein that interacts with LFA-1 on the T-cells to allow infection and we discuss the alternative mechanisms of how SARS-CoV-2 infects T-cells, appearing to mimic what HIV viruses do.

Described content:
HIV inserts in Spike: https://www.biorxiv.org/content/10.1101/2020.01.30.927871v1.full
Infection of lymphocytes:
https://www.nature.com/articles/s41392-022-00919-x
LFA-1 SARS-CoV-2 structure:
https://www.sciencedirect.com/science/article/pii/S2589004221001553
HIV LFA-1 binding:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC114007/

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Dr. Raszek Credentials: https://merogenomics.ca/en/about/
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