Long Story Short Episode 67: Gut Microbiota-Targeted Diets Modulate Human Immune Status

This amazing study demonstrates the influence of plant-based (high-fiber) and/or fermented food diets on our immune system. Researchers found that fermented foods like yogurt, kimchi, and kombucha caused a reduction of 19 cytokines including IL-6, IL-12b, and IL-10. This reduction may potentially lead to reduction in chronic inflammation. Let's review this study.

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References (August 18, 2023)

Gut Microbiota-Targeted Diets Modulate Human Immune Status - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9020749/

Figure - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9020749/figure/F6/

Interleukin-6 as a Multifunctional Regulator: Inflammation, Immune Response, and Fibrosis - Ernest Choy, Stefan Rose-John, 2017
https://journals.sagepub.com/doi/10.5301/jsrd.5000265#:~:text=IL%2D6%20is%20produced%20by,cells%2C%20fibroblasts%2C%20and%20hepatocytes.

Role of Interleukin 10 Transcriptional Regulation in Inflammation and Autoimmune Disease - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3410706/#:~:text=In%20vivo%2C%20major%20sources%20of,granulocytes%20like%20neutrophils%20and%20eosinophils.

Regulation of IL-10 and IL-12 production and function in macrophages and dendritic cells - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754024/#:~:text=Interleukin%2D12%20signaling,dendritic%20cells%20(DCs)%202.

Interleukin-10 production by effector T cells: Th1 cells show self control - PMC
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2118719/

Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only. Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.
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