The Science Behind Amyloid Beta Deposition | Alzheimer's Disease

In this video, join Dr. Sanjeev Goel as he delves into the fascinating science behind amyloid beta deposition and its connection to Alzheimer's disease. Discover the historical origins of Alzheimer's research, the role of genetic mutations in amyloid buildup, and the intricate cascade of events that lead to neuroinflammation and cognitive decline.

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Alzheimer's disease:
Alzheimer's is a memory-related disease with no cure.
Risk factors include family history and age.
Ongoing research seeks better treatments.
Alzheimer's affects patients and caregivers deeply.
Early diagnosis aids symptom management.

Amyloid beta deposition:
Amyloid beta buildup marks Alzheimer's.
Imaging detects amyloid plaques.
Understanding helps treatment development.
Researchers target prevention strategies.
Reducing amyloid buildup is vital.

Genetic mutations:
Mutations increase Alzheimer's risk.
Inherited mutations raise the risk.
Genetic counseling assesses risk.
Research explores treatment targets.
Alzheimer's may have genetic links.

Neuroinflammation:
Neuroinflammation harms the nervous system.
It's linked to Alzheimer's and other diseases.
Microglia activation drives inflammation.
Lifestyle affects neuroinflammation levels.
Reducing inflammation may slow disease.

Blood test for Alzheimer's:
FDA-approved blood test aids early diagnosis.
Measures amyloid beta ratios in plasma.
High amyloid beta 42 ratio raises risk.
Convenient testing assesses Alzheimer's risk.
Early detection enables timely interventions.

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TIMESTAMP
00:00 - Introduction
00:23 - Historical Background
01:12 - Amyloid Beta Buildup
02:25 - Genetic Mutations
03:41 - Early Signs of Amyloid Deposition
04:59 - The Amyloid Cascade

#alzheimersdisease #geneticmutation #amyloidbetadeposition