Episode 2: Obesity is a Brain Disorder

Lots of peeps want to lose weight this New Years. Heck, they’ve been trying every New Years for the last few.

Why don’t they succeed? They fundamentally don’t understand this issue, neither does their doctor

00:29 What is the root of the obesity epidemic?
02:05 What are the systems governing weight loss? 
03:19 Is obesity due to weight loss or hormones?
04:07 What is leptin and melanocortin and how does it play into obesity? The leptin/melanocortin pathway
06:20 Genetic causes of obesity
07:14 What inputs affect the leptin-melanocortin pathway? 
09:13 How does light play into regulating obesity?
12:08 Other important hormones besides leptin and melanocortin? Cortisol and melatonin
13:45 Light diet
15:40 Standard american diet, processed foods, macronutrients and micronutrients
16:52 What is the best diet to follow
17:25 Optimal diet summary (more in episode 3)
18:52 Three main categories leading to obesity and weight loss
19:19 Set point theory
20:58 Lac-Phe system
21:51 Obesity and genes, obesogenic vs restrictive environment