Why People Get Gout & What To Do About It (2024)

Why People Get Gout & What to Do (2024)

- Gout is the accumulation of Uric Acid crystal clumps (Tophi) in
joints, soft tissues, ankles, knees, organs, and foot, especially (Big toe)
(Monosodium Urate)

- Excessive Fructose & Alcohol consumption. = High
- ATP = AMP = IMP = XMP = GMP = GDP / GTP = Xanthine = Uric Acid
- Adenotriphosphate, Monom InosineMono, Guanosine Mono, Di, Tri

- Dr. Richard Johnson on the Polyol pathway
- Glucose can be converted into Fructose
- Glucose = Sorbitol = Fructose = Xylitol = Xylulose = Glyceraldehyde
- Enters the Purines Metabolism Cycle.

- Organs, Seafoods, Meats, and some veggies breakdown into Purines. = Low
- Enters the Purines Metabolism cycle.

- Uric Acid Filtered by Kidneys and then peed out.
- ~90% Reabsorbed for Purines (DNA, RNA, ATP Recycling) (URAT1 & OAT4)
- Not very soluble.
- If not, Monosodium Urate (MSU) deposits form.
- Immune System activates using Phagocytosis / Macrophages
- Synovial Fluids Lysozymes
- Inflammation, Immune System trying its best to detox Uric Acid.

- Molybdenum connection = activates Xanthine Oxidase
- If deficiency or Allopurinol (Inhibits Xanthine Oxidase),
less Uric Acid but creates Xanthine Kidney Stones (Xanthuria)
- Allopurinol = High chance of Liver Injury and High Mortality.
- Less Nitric Oxide, Endothelial Function of Blood Vessels,
Phase 1 & 2 Liver detox (Sulfite & Aldehydes), Hypoxia adaptation, Iron Homeostasis.

What to do?
- Reduce Sugar, Carbs, Fruits, and Alcohol. = Too much may cause excessive Uric Acid.
- Less uric acid = Lower Glycemic Index Foods
- Gives the Kidneys more time to filter Uric Acid to be peed out.
- Drink more water. 70oz-100oz daily.
- More Potassium, this electrolyte helps excrete more Uric Acid.
- More Zinc , ZIP8 Transporter moves Uric Acid to Kidneys.
- Zinc deficiency linked to higher Uric Acid levels.
#gout #uricacid #uricaciddiet #uricacidcrystals #newstartnutritionconsulting

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Disclaimer: I am not a Medical Doctor or a Dietician. I am a Nutritional Therapy Practitioner and Nutrition Researcher. Therefore, I legally do not Treat, Diagnose, Prevent, or Cure people. My advice is to not be construed as such and is my opinion. I educate people on the following topics above. My advice is best tailored to my clients. If you are not my client then any advice given should be discussed with your professional healthcare provider.