Methylation - Part 1 (MTHFR) - MTHFR KETO CARNIVORE

MTHFR gene SNP rs1801133 (C677T) "homocysteine levels" & rs1801131 (A1298C or E429A) Unlike MTHFR C677T, this mutation does not lead to elevated homocysteine levels.

MTHFR enzyme activity, homozygous rs1801133(T;T) individuals have only 30% activity, rs1801133(C;T) heterozygotes have 65% activity, compared to the common genotype, rs1801133(C;C).

First Published on YouTube on 4 June 2020