How Growth Hormone Harms Thyroid Function

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Citations:
GRUNFELD, C., SHERMAN, B. M., & CAVALIERI, R. R. (1988). The acute effects of human growth hormone administration on thyroid function in normal men. The Journal of Clinical Endocrinology & Metabolism, 67(5), 1111-1114.https://academic.oup.com/jcem/article-abstract/67/5/1111/2652117

Lippe, B. M., Van Herle, A. J., Lafranchi, S. H., Uller, R. P., NORMAN, L., & Kaplan, S. A. (1975). Reversible hypothyroidism in growth hormone-deficient children treated with human growth hormone. The Journal of Clinical Endocrinology & Metabolism, 40(4), 612-618. https://academic.oup.com/jcem/article-abstract/40/4/612/2684939

Wyatt, D. T., Gesundheit, N., & Sherman, B. (1998). Changes in thyroid hormone levels during growth hormone therapy in initially euthyroid patients: lack of need for thyroxine supplementation. The Journal of Clinical Endocrinology & Metabolism, 83(10), 3493-3497. https://academic.oup.com/jcem/article-abstract/83/10/3493/2865448

Seminara, S., Stagi, S., Candura, L., Scrivano, M., Lenzi, L., Nanni, L., ... & Chiarelli, F. (2005). Changes of thyroid function during long-term hGH therapy in GHD children. A possible relationship with catch-up growth?. Hormone and metabolic research, 37(12), 751-756. https://www.thieme-connect.com/products/ejournals/abstract/10.1055/s-2005-921104

Porretti, S., Giavoli, C., Ronchi, C., Lombardi, G., Zaccaria, M., Valle, D., ... & Eli Lilly & Co. B9R-EW-GDED Italian Study Group. (2002). Recombinant human GH replacement therapy and thyroid function in a large group of adult GH-deficient patients: when does L-T4 therapy become mandatory?. The Journal of Clinical Endocrinology & Metabolism, 87(5), 2042-2045.https://academic.oup.com/jcem/article-abstract/87/5/2042/2846673

Jørgensen, J. O. L., Møller, J., Laursen, T., Ørskov, H., Christiansen, J. S., & Weeke, J. (1994). Growth hormone administration stimulates energy expenditure and extrathyroidal conversion of thyroxine to triiodothyronine in a dose‐dependent manner and suppresses circadian thyrotrophin levels: studies in GH‐deficient adults. Clinical Endocrinology, 41(5), 609-614. https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1365-2265.1994.tb01826.x

Klinger, B., Ionesco, A., Anin, S., & Laron, Z. (1992). Effect of insulin-like growth factor I on the thyroid axis in patients with Laron-type dwarfism and healthy subjects. European Journal of Endocrinology, 127(6), 515-519. https://eje.bioscientifica.com/view/journals/eje/127/6/acta_127_6_008.xml

Jørgensen, J. O., Møller, J., Skakkebæk, N. E., Weeke, J., & Christiansen, J. S. (1992). Thyroid function during growth hormone therapy. Hormone Research in Paediatrics, 38(Suppl. 1), 63-67. https://thyroidresearchjournal.biomedcentral.com/articles/10.1186/1756-6614-3-2

#gh #thyroid #growth