What is COLLAGEN?

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What does COLLAGEN mean? COLLAGEN meaning - COLLAGEN definition - COLLAGEN explanation. What is the meaning of COLLAGEN? What is the definition of COLLAGEN? What does COLLAGEN stand for? What is COLLAGEN meaning? What is COLLAGEN definition?

Collagen is the main structural protein in the extracellular space in the various connective tissues in animal bodies. As the main component of connective tissue, it is the most abundant protein in mammals, making up from 25% to 35% of the whole-body protein content. Depending upon the degree of mineralization, collagen tissues may be rigid (bone), compliant (tendon), or have a gradient from rigid to compliant (cartilage). Collagen, in the form of elongated fibrils, is mostly found in fibrous tissues such as tendons, ligaments and skin. It is also abundant in corneas, cartilage, bones, blood vessels, the gut, intervertebral discs and the dentin in teeth. In muscle tissue, it serves as a major component of the endomysium. Collagen constitutes one to two percent of muscle tissue, and accounts for 6% of the weight of strong, tendinous muscles. The fibroblast is the most common cell that creates collagen.

Gelatin, which is used in food and industry, is collagen that has been irreversibly hydrolyzed. Collagen also has many medical uses in treating complications of the bones and skin.

The name collagen comes from the Greek kolla, meaning "glue", and suffix gen, denoting "producing". This refers to the compound's early use in the process of boiling the skin and sinews of horses and other animals to obtain glue.