Understanding IBS Causes, Symptoms, and management

Irritable Bowel Syndrome (IBS) is a common gastrointestinal disorder characterized by a group of symptoms that occur together, including repeated pain in your abdomen and changes in your bowel movements, which may be diarrhea, constipation, or both. Understanding IBS involves delving into its pathogenesis, identifying its causes, recognizing symptoms, and exploring effective management and prevention strategies.

Pathogenesis

The pathogenesis of IBS is multifactorial and not entirely understood, but it involves a complex interaction of several factors:

Gut-Brain Axis: The communication between the gastrointestinal tract and the central nervous system is often disrupted in IBS patients.
Motility Issues: Abnormal gastrointestinal motility can lead to either increased transit time (constipation) or decreased transit time (diarrhea).
Visceral Hypersensitivity: Individuals with IBS often have an increased sensitivity to pain within the gastrointestinal tract.
Microbiome Imbalance: Changes in the gut microbiota may contribute to the symptoms of IBS.
Immune System Activation: Low-grade inflammation and immune activation are sometimes observed in IBS patients.

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