Self-Amplifying mRNA COVID Vaccine Approved for Mass Production

In a groundbreaking move, Japan has become the first country to authorize a new type of vaccine—self-amplifying mRNA (sa-mRNA). Meiji Seika Pharma's Kostaive sa-mRNA COVID vaccine, gaining government approval on November 28, introduces a unique approach in vaccine technology. Unlike traditional mRNA vaccines, this variant incorporates genes for RNA replication, opening avenues for exploration in COVID-19 vaccination.