Do Root Canals Cause Cancer? 🦷

The answer isn’t straightforward, but it’s time to ask the hard questions. Medicine today often discourages questions and curiosity—but we need to collect and connect the dots.

* Infectious Diseases and Cancer: It’s well-established that viruses, bacteria, parasites, and fungi can cause cancer. The gut microbiome is also linked to cancer initiation and progression.

* The Tumor Microbiome: Certain bacteria from the gut can even seed into tumor environments, like in pancreatic cancer, aiding cancer growth and immune evasion.

* Root Canal Bacteria: A recent 2023 study found that bacteria in root canals can lead to local immune dysfunction, causing chronic inflammation and systemic immune suppression. This has been linked to autoimmune diseases like Lupus and Sjogren’s, and if it can happen with autoimmune conditions, cancer isn’t out of the question.

The precedent exists—though there’s no conclusive link yet. Keep questioning, keep researching, and remember: true healthcare is about empowering you with the knowledge you need to make informed choices.

Supporting Evidence:

Johnson S, Morad G, Ajami N, et al 838 The role of microbiota in metastatic brain tumors Journal for ImmunoTherapy of Cancer 2021;9:doi:
10.1136/jitc-2021-SITC2021.838

Lin B, Ye Z, Ye Z, Wang M, Cao Z, Gao R, Zhang Y. Gut microbiota in brain tumors: An emerging crucial player. CNS Neurosci Ther. 2023 Jun;29 Suppl 1(Suppl 1):84-97. doi: 10.1111/cns.14081.SITC2021.838

Feng Y, Hu X, Zhang Y, Wang Y. The Role of Microglia in Brain Metastases: Mechanisms and Strategies. Aging Dis. 2024 Feb 1;15(1):169-185. doi: 10.14336/AD.2023.0514.

Zitvogel L, Ma Y, Raoult D, et al. "The Microbiome in Cancer Immunotherapy: Diagnostic Tools and Therapeutic Strategies." Science. 2021.

Erny D, Hrabě de Angelis AL, Prinz M. "Communications between the Microbiome and the Brain." Nature Neuroscience. 2020.

Sampson TR, Mazmanian SK. "Control of Brain Immune Signaling by Gut Microbiota During Health and Disease." Frontiers in Oncology. 2021.

Sobieszczański J, Mertowski S, Sarna-Boś K, et al. Root Canal Infection and Its Impact on the Oral Cavity Microenvironment in the Context of Immune System Disorders in Selected Diseases: A Narrative Review. Journal of Clinical Medicine. 2023 Jun;12(12):4102. DOI: 10.3390/jcm12124102.

Papa V, Schepis T, Coppola G, Chiappetta MF, Del Vecchio LE, Rozera T, Quero G, Gasbarrini A, Alfieri S, Papa A. The Role of Microbiota in Pancreatic Cancer. Cancers. 2023; 15(12):3143. https://doi.org/10.3390/cancers15123143

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