1 year ago

212

Health & Science @Campbellteaching @dr.kathleenruddy1734

10/20/2024
Ivermectin, a potential anti-cancer drug derived from an antiparasitic drug, https://www.ncbi.nlm.nih.gov/pmc/arti... Mechanisms of action

IVM induces different programmed cell death patterns in different tumor cells,

The main form of IVM-induced programmed cell death is apoptosis.

Apoptosis

Programmed cell death

Autophagy

Lysosomal-dependent form of programmed cell death.

Pyroptosis

Inflammatory cell death induced by inflammasomes.

Kathleen T Ruddy, MD / 1

https://rumble.com/v4vk4pw-oncologist...

/ docruddy

https://rumble.com/v4vk4pw-oncologist... Types of Cancer

Breast Cancer

A malignant tumor that results from gene mutation in breast epithelial cells

Cancer of the Digestive System

Stomach cancer is one of the most common malignant tumors worldwide.

Hepatocellular carcinoma is the fourth leading cause of cancer death worldwide.

Cancer of the Urinary Tract

Renal cell carcinoma is a fatal malignant tumor of the urinary system that arises from renal tubular epithelial cells.

Prostate cancer is a malignant tumor derived from prostate epithelial cells

Hematologic cancer

Leukemia is a type of malignant clonal disease caused by abnormal hematopoietic stem cells

Cancer of the reproductive system

Cervical cancer is one of the most common gynecological malignancies

Ovarian cancer is a malignant cancer that lacks early clinical symptoms and responds poorly to therapy.

Glioma of the brain

Glioma is the most common brain tumor

Glioblastoma, median survival of 14-17 months

Cancer of the respiratory tract

Nasopharyngeal carcinoma is a malignant tumor derived from epithelial cells of the nasopharyngeal mucosa.

Lung cancer has the highest morbidity and mortality among cancers

Melanoma

The most common malignant skin tumor with a high mortality rate.

Other Papers

Ivermectin suppresses tumor growth and metastasis by knocking down PAK1 in esophageal squamous cell carcinoma https://www.ncbi.nlm.nih.gov/pmc/arti... The antitumor effects of ivermectin at clinically feasible concentrations support its clinical development as a repositioned anticancer drug https://pubmed.ncbi.nlm.nih.gov/32474... Ivermectin converts cold tumors to hot and acts synergistically with immune checkpoint blockade to treat breast cancer https://www.nature.com/articles/s4152... Abstract 2320: Ivermectin suppresses pancreatic cancer via mitochondrial dysfunction https://aacrjournals.org/cancerres/ar... Video Reviews • h360 HealthTalk: Dr. Sophie Bartsich ...