S4E18: Receptor Deficiency Disease| NURTURING & ACTIVATION | Special Guest: Michelle T.

S4E18: Receptor Deficiency Disease

Severe pain often requires opioids to trigger and engage the seven receptors in the brain that help relieve pain signals and receive neurotransmitters for relief management. The three major neurotransmitters involved are endorphins, dopamine, and GABA. There are also four secondary neurotransmitters: serotonin, cannabinoid, methyl d-acetate, and adrenergic.

Receptor Deficiency Disease has largely been overlooked due to the push for external interventions, such as implanted stimulators, morphine pumps, and even the use of gabapentin, or baclofen, to replace benzodiazepines. This shift has also included the use of extended-release opioids like prescription fentanyl citrate and extended-release morphine/oxycodone.

It is crucial to return to treating deficient receptors by nurturing and activating them, particularly in intractable pain clinics.

Additionally, there’s a discussion around the concept of viruses as parasites. What should we do about a virus that seeks to nest in our tissues or reactivate? This is especially pertinent since many patients with intractable pain syndrome (IPS) have Epstein-Barr virus (EBV). In Dr. Tennant's experience, only two or three out of over two dozen patients he evaluated had adequate pain control, which is concerning.

Conditions such as complex regional pain syndrome (CRPS) require careful consideration, and it’s important to clarify the distinction between "end-orphin" and "end-m-orphin-e."

Supportive supplements such as those for gut health, including prebiotics, probiotics, and postbiotics, as well as natural remedies like aloe vera and moringa, can also play a role in pain management by keeping the microbiome healthy. Our gut is our 2nd brain.

There is a concerning attitude among some pharmacists, "Too bad, let them die," reflecting a lack of compassion for those in pain.

Finally, discussions are ongoing about the evidently ignored CO House Bill that was unanimously passed for people with intractable pain, as well as ongoing issues with insurance company practices.

Mark your calendar for a vitally important meeting on December 3rd, hosted by Dr. Mark Ibsen, Dr. Jeffrey Singer, Kate Nicholson, Brandy Stokes, and Ron Chapman.