Using Transdermal Nicotine to Resolve Long-Haul Covid Symptoms

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It was recognized early on that tobacco smokers seemed to have surprisingly less trouble with Covid-19 than nonsmokers.

What has been discovered since then is the effect of nicotine on the nicotinic acetylcholine receptors (nAChRs), receptors the SARS-CoV-2 virus utilizes to access its host. We used to think it was the ACE2 receptors that mattered, and they certainly do, but this study clearly demonstrates the effect of transdermal nicotine therapy to quickly resolve multiple long-haul Covid symptoms:

"Abstract
Following a SARS-CoV-2 infection, many individuals suffer from post-COVID-19 syndrome. It makes them unable to proceed with common everyday activities due to weakness, memory lapses, pain, dyspnea and other unspecific
physical complaints. Several investigators could demonstrate that the SARS-CoV-2 related spike glycoprotein (SGP) attaches not only to ACE-2 receptors but also shows DNA sections highly affine to nicotinic acetylcholine receptors
(nAChRs). The nAChR is the principal structure of cholinergic neuromodulation and is responsible for coordinated neuronal network interaction. Non-intrinsic viral nAChR attachment compromises integrative interneuronal com
munication substantially. This explains the cognitive, neuromuscular and mood impairment, as well as the vegetative symptoms, characterizing post-COVID-19 syndrome. The agonist ligand nicotine shows an up to 30-fold higher
affinity to nACHRs than acetylcholine (ACh). We therefore hypothesize that this molecule could displace the virus from nAChR attachment and pave the way for unimpaired cholinergic signal transmission. Treating several individuals
suffering from post-COVID-19 syndrome with a nicotine patch application, we witnessed improvements ranging from immediate and substantial to complete remission in a matter of days." View study here: https://www.wondrousroots.org/_files/ugd/a7455d_88a52becad864cf4af1e977b81edfcc9.pdf?index=true

I also discuss scientific justification for the off-label use of nicotine patches for other diseases, such as Parkinson's, Alzheimers, and more.