Klotho: Endogenous Anti-Aging Protein

The information presented in this webinar is found here: https://www.wondrousroots.org/klotho

Klotho is a transmembrane and circulating protein that plays a key role in aging and longevity. It functions as a co-receptor for fibroblast growth factor 23 (FGF23), regulating phosphate and calcium metabolism, but it also has independent antioxidant, anti-inflammatory, and neuroprotective effects. Higher levels of klotho are associated with extended lifespan, enhanced cognitive function, and reduced age-related degeneration, while its decline with age contributes to oxidative stress, inflammation, and tissue damage. Researchers are exploring ways to boost klotho expression as a potential anti-aging strategy.