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巴金森氏症元兇 發病關鍵在腸胃
7 months ago
3
2025年2月13日
為什麼喝咖啡能預防巴金森氏症?或許這個研究可以解答。刊登在新的《細胞期刊》中的研究指出,大家都以為巴金森氏症的毛病是出現在腦部,但新的研究卻指出,發病原因可能是在腸胃道!
這項研究是由美國加州理工學院的研究人員所發現,研究人員培育兩組生成過多的α突觸核蛋白(alpha-synuclein)的實驗老鼠,這種蛋白被認為是引起巴金森氏症的原因之一,其中一組老鼠的腸胃菌群是完整的,而另一組則是無菌的實驗鼠。
結果顯示,無菌的實驗鼠不僅未發生巴金森氏症病變,而且跑步等各種運動機能測試都很好。但在研究人員餵食部分無菌實驗鼠腸道菌群分解食物纖維時產生的短鏈脂肪酸,另外一部分則移植從巴金森氏症患者糞便中取得的腸道菌落,結果這兩組老鼠都發生巴金森氏症的症狀。
研究人員表示,腸道微生物是巴金森氏症發生的重要誘因,腸道菌群的組成變化,可能促使或導致運動機能惡化。研究也發現,約有75%的巴金森氏症患者有腸胃障礙,其中最常見的症狀是便秘。未來治療或預防巴金森氏症,或許應從腸道著手更有效。
更多其他精彩話題內容:
https://www.notion.so/7023b7b2cd5d4f5082c4aa7fb0fdcd1a?v=d4926f105c56473cbc55a3abe991aeac&pvs=4
https://scalloped-capybara-acc.notion.site/Health-Today-718e21949e6245e9b2e4d0acc93ed0e4
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