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数千人可能受益于乳腺癌新疗法
6 months ago
6
英国晚期乳腺癌患者将迎来新的治疗希望。
英国国立卫生研究院注册营养师和皇家马斯登生物医学研究中心支持的一种新疗法将为晚期乳腺癌患者带来福音。该疗法结合了Capivasertib片剂和氟维司群激素疗法,适用于HR阳性、HER2阴性且已扩散的乳腺癌患者,要求患者具有PIK3CA、AKT1或PTEN基因的特定变异,并在之前的激素治疗后复发或恶化。
临床试验显示,该疗法可延缓癌症进展,患者平均多活了约四个月,且癌症未恶化。英国国家卫生与临床优化研究所已批准该疗法,英格兰约有1100人可能符合条件。Capivasertib通过阻断癌细胞生长和分裂所需的信号来减缓或阻止癌症生长,为那些携带特定基因突变的患者带来了希望。
2020年,英格兰有超过4万人被诊断出患有乳腺癌,约15%的患者确诊时已处于晚期。新疗法的出现为这些患者提供了更多的治疗选择。
Edited by Kun Liang
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