Dr. Goodenowe - Plasmalogens for Brain Health

Dr. Goodenowe - Plasmalogens for Brain Health and Neurodegenerative Diseases
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CHAT
00:08:21 wayne: jILL'S bOOK: "Unexpected"
00:08:52 wayne: Unexpected: Finding Resiliance Through Functional Medicine
00:13:46 UserDoris: Thank you Wayne.
00:14:35 KellyV: am I late to the party?
00:17:54 wayne: Have you studied anything about Galectin-3 which I read is being claimed as potentially modulating immune responses by binding to glycoproteins nthe surface of immune cells, affecting their activation, differentiation, and cytokine production. I'm reading that it is possibly playing a role in neuroinflammation and neurodegenerative diseases, including ALZ
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00:18:59 wayne: I read that Galectin 3 can promo
00:20:22 wayne: .... Gal 3 can promote pro-inflammatory activation of microglia, leading to the release of inflammatory cytokines which contribute to neuronal damage.. Comments?
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00:23:06 wayne: I saw Gal-3 detected in CSF and brains tissues of ALZ patients, suggesting a biomarker. of disease... (also binds to amyloid beta which I understand led to foing down some blind alleys after the Photo Shopped Nature paper.
00:27:37 UserDoris: Dr. Isaac Eliaz taught about Galectin-3 that drives many chronic metabolic diseases. It is involved in glucose homeostasis, immune responses, and inflammation, and its expression is often elevated in individuals with metabolic diseases.
00:34:37 Henry Katz: This paper on TC: https://www.nature.com/articles/s41598-018-38461-y
00:44:55 Susan: Our bodies can make Choline?
00:47:06 Jeffrey: Replying to "Our bodies can make ..."

The body produces some Choline in the liver but the body, unfortunately, does not produce enough.
00:47:42 KellyV: Replying to "Our bodies can make ..."

Yes, the human body can make choline, but not in sufficient amounts to meet all of its needs. Therefore, choline is considered an essential nutrient, meaning you must get a significant portion of it from your diet.
Here's how it works:
The body synthesizes a small amount of choline in the liver via the PEMT (phosphatidylethanolamine N-methyltransferase) pathway.
However, this endogenous production is not enough to support optimal health, especially in situations of high demand (e.g., pregnancy, lactation, liver health, brain development).
Dietary sources of choline:
Eggs (especially the yolk)
Beef liver
Chicken
Fish
Soybeans
Cruciferous vegetables (like broccoli and Brussels sprouts)
Why choline is important:
It's critical for brain development, cell membrane structure, methylation reactions, and neurotransmitter synthesis (acetylcholine).
In summary: Your body makes some choline, but you need to eat foods rich in choline to meet your full daily requirement.
00:48:01 aschwartz: Replying to "Our bodies can make ..."

Can you repeat the 3 M's
00:48:20 Henry Katz: Replying to "Our bodies can make ..."

membrane, mitochondria, methyl-transferase
00:48:46 aschwartz: Replying to "Our bodies can make ..."

TY!
00:52:37 Carole: How to increase plasmalogens
00:53:08 KellyV: www.prodrome.com for plasmalogen precursors
00:55:59 Carole: Why are we told to keep Omega 9s to a minimum if they are good for the brain?
00:56:19 Susan: TY Kelly for info on choline. I order special range free eggs to help with this.
00:56:30 KellyV: Reacted to "TY Kelly for info on..." with 👍
00:56:37 Carole: Reacted to "TY Kelly for info on…" with 👍
00:56:44 Dr. Thomas Lewis: Carole: Dogma, and the lumping of them with the 6s.
00:57:44 Carole: We are told Omega 3s are the most important.
00:58:09 Dr. Thomas Lewis: Not true - 6/3 ratio should be 3/1
00:58:22 Dr. Thomas Lewis: 3s for brain -
00:59:20 Carole: Where do the 9s fit in the ratio?
01:00:30 Susan: Good Krill Oil?
01:07:54 Kenton Crowley, PharmD: This is such a great conversation!
01:08:15 Jeffrey: Reacted to "This is such a great..." with 👍
01:08:21 UserDoris: What did he say about fatty acids and diabetes?
01:08:33 KellyV: Reacted to "This is such a great..." with 👍
01:10:26 Susan: I think I heard Dr. G say there is a blood test for Colon Cancer?
01:12:58 Henry Katz: https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(05)60761-1/abstract
01:30:16 Henry Katz: Please share link for slides
01:33:14 WG: Also take Phos choline?
01:33:58 KellyV: the slides are in this lecture: https://wistia-1577512538.wistia.com/medias/elb009f2bi
01:35:29 Susan: Hard to understand this but Thank You for another great Session.
01:36:05 KellyV: please visit www.drgoodenowe.com for more information
01:36:09 Dr. Thomas Lewis: Me too Susan: I will have to listen to this and the lecture found through the link - a couple of times.
01:36:19 Dr. Thomas Lewis: Very high level scientist.
01:36:59 Susan: Amen!
01:37:36 KellyV: Reacted to "Very high level scie..." with 👍
01:38:44 UserDoris: I have scratch my head Susan, because I cant get the gist of it all and I try to take notes but I cant understand it to note it. But I will watch it a couple of times when it is released to us.
01:38:56 OHIO AMY 🇺🇸: Please Repeat what your protocol is for an elderly Parkinson patient -
01:40:55 Maura: Reacted to "Very high level scie…" with 👍
01:45:21 UserDoris: What did he say about mutation of the heart?
01:45:26 Carol’s iPad: What is takeaway for nutrition, activity, and supplementation ?
01:46:06 KellyV: Here is the file of Dr. Goodenowe's slides to his presentation
01:46:52 UserDoris: What did he say about gene mutation of the heart?
01:47:38 Dr. Thomas Lewis: I will try to publish the lecture tomorrow. I need to listen to it again.
01:48:11 KellyV: Reacted to "I will try to publis..." with 👍
01:50:35 UserDoris: If one has gut issues, making smoothies with veggies and fruit is okay, right?
02:04:30 Dr. Thomas Lewis: Doris - too much sugar!
02:05:20 OHIO AMY 🇺🇸: Wow amazing -
02:05:23 Henry Katz: Have you spoken with Dr. Whitcomb who released this book: https://fixyourbrokenbrain.com/ this February? He has undergone your plasmalogen protocol.
02:05:39 Jessica Castillo: Reacted to "Have you spoken with..." with ❤️
02:05:59 laurathompson: What amount of time of treatment did these improvements occur?
02:06:02 Jessica Castillo: absolutely!
02:07:07 Henry Katz: He claims increase in brain volume over time with volumetric MRI.
02:07:24 Kenton Crowley, PharmD: Reacted to "He claims increase i..." with 👍
02:07:26 laurathompson: Can an APOE3/3 be improved as well?
02:07:31 Jessica Castillo: Replying to "Have you spoken with..."

Dr. Whitcomb is one of our Elite doctors! Dr. Goodenowe reviewed and praised his book!
02:07:42 KellyV: Reacted to "Dr. Whitcomb is one ..." with 👍
02:07:42 iPhone: Reacted to "Have you spoken with…" with ❤️
02:07:55 KellyV: Reacted to "Have you spoken with..." with 👍
02:08:29 laurathompson: What is IGG?
02:08:44 wayne: What tests followed by possible preventative treatment options do you offer for thothose who are not no symptomatic for this disease?
02:09:06 Henry Katz: Replying to "What is IGG?"

Immunglobulin type G.
02:09:18 Hether: There's nothing natural that would do this same thing? Just because I don't like relying on pills for life.
02:09:38 Tina: Thanks for bringing Dr. Goodenowe to the forum. Fascinating research!
02:09:47 KellyV: Reacted to "Thanks for bringing ..." with 👍
02:09:49 Jessica Castillo: Reacted to "Thanks for bringing ..." with ❤️
02:09:57 Maura: Reacted to "Thanks for bringing …" with 👍
02:10:17 Joe Connolly: Reacted to Thanks for bringing ... with "👍"
02:10:17 wolfe: when will the new testing be available
02:10:55 OHIO AMY 🇺🇸: Please Repeat what your protocol is for an elderly Parkinson patient -
02:12:58 Fireflies.ai Notetaker Paul: The meeting schedule is about to end.
Action Items for this meeting:
- Call David Perlmutter regarding luteolin and tart cherry. @Dayan Goodenowe
- Prepare a PowerPoint presentation for the group. @Dayan Goodenowe
- Show MRI technologies that can fully digitize the brain. @Dayan Goodenowe
- Publish a blog post with a short blurb about the discussed treatment and protocol. @Dr. Thomas Lewis
- Go over the protocol with Dr. Thomas Lewis and discuss how it is being used clinically. @M Carter
02:13:44 Henry Katz: Replying to "Have you spoken with..."

Are the elite practitioners listed yet? I see the applic: https://prodrome.com/pages/elite
02:14:25 Hether: Where is this blog found?
02:14:37 Dr. Thomas Lewis: Blog is on
02:14:43 Dr. Thomas Lewis: www.healthrevivalpartners.com
02:15:03 Hether: thanks
02:15:10 KellyV: Replying to "Have you spoken with..."

Practitioner Directory
02:15:13 OHIO AMY 🇺🇸: Does that have to be an in person test or blood test
02:15:45 Marjorie Trebino’s iPad (2): Thank you
02:16:00 Jessica Castillo: Replying to "Does that have to be..."

contact [email protected]
02:17:12 laurathompson: My husband has been on the prodrome therapy at full dose for 6 weeks
02:17:39 KellyV: Reacted to "My husband has been ..." with 👍
02:18:11 Jessica Castillo: Reacted to "My husband has been ..." with ❤️
02:18:23 Fireflies.ai Notetaker Paul: Attention: Recording will stop in 2 minutes. You can re-invite to continue recording.
02:21:15 wayne: how durable is laser light therapy?
02:21:21 David B.: Wow… what a great meeting ! Very much appreciated .
02:22:06 KellyV: Reacted to "Wow… what a great me..." with 👍
02:22:35 Maura: Replying to "Have you spoken with…"
It’s only effort until it’s routine 🥰
02:23:16 KellyV: Reacted to "It’s only effort unt..." with ❤️
02:24:53 Henry Katz: Reacted to "Practitioner Directo..." with 👍