Colon cancer in the young

Colon cancer

Breast, prostate, lung, bowel, melanoma, kidney, lymphoma

Cause of cancer deaths, lung bowel

US data, 10.5% of newly diagnosed colorectal cancers now occur in people younger than 50

Expected to rise to 15% by 2030

https://www.cancer.org/cancer/types/colon-rectal-cancer/causes-risks-prevention/risk-factors.html

Colorectal cancer is rising among people who are younger than age 50, and the reason for this remains unclear.

https://pmc.ncbi.nlm.nih.gov/articles/PMC9177054/

Index of suspicion at younger age

Anaemia, (red flag), SOBE, fatigue, pallor

Abdominal pain, bloating

Diarrhoea or constipation

Change in normal bowel habit, (looser, more or less often), 3 weeks

PR bleed, mixed, streaked, dark and tarry

Pencil stools

Feeling of fullness after passing stool

Straining

Abdo or back passage pain

Lumps or obstruction

Weight loss

DVT

Aetiology

Obesity

Physical activity

DM2

Diet

Microbiome, probiotics, prebiotics

Vitamin D

Smoking

Alcohol

Microplastics

Personal and family history

Adenomatous polyps

Inflammatory bowel disease

Lynch syndrome, hereditary non-polyposis colon cancer or (HNPCC)

mRNA injections