Pfizer-BioNTech mRNA Vaccine Elevates Inhibin B in Ovarian Granulosa Cells—Potential Menstrual and Fertility Impacts

The dialogue discusses an in vitro study of the Pfizer-BioNTech mRNA COVID-19 vaccine on human ovarian granulosa cells. The researchers found no cell death or loss of viability, but did observe a >200 % increase in inhibin B expression, which normally suppresses FSH release. Since FSH drives follicle growth and ovulation, elevated inhibin B could theoretically interfere with the menstrual cycle and fertility. One speaker reacts with alarm, calling it “sad” that the vaccine might act “at the root” of the reproductive process.