The Liver & Weight Connection: New Curcumin Research Ep. 1246 JUN 2025 Summary

A 12-month, double-blind, placebo-controlled trial has revealed that daily supplementation with 1500 mg of curcumin offers significant benefits for both liver health and weight management in individuals with Type 2 Diabetes and Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD). The study demonstrated remarkable improvements in liver health markers for the curcumin group compared to the placebo group. Specifically, after 12 months, participants taking curcumin had significantly lower liver stiffness (4.2 kPa vs 6.9 kPa) and significantly less liver fat, as measured by the Controlled Attenuation Parameter (223 dB/m vs 292 dB/m). Fatty liver-associated indicators such as the Fatty Liver Index (FLI) and Hepatic Steatosis Index (HSI) also showed significant reductions.
In addition to these direct liver benefits, the curcumin group also experienced significant improvements in body composition. Body Mass Index (BMI) was significantly reduced from the 6-month mark onward. At the end of the study, the median BMI for the curcumin group was 25.97 kg/m², notably lower than the placebo group's 27.70 kg/m². Furthermore, significant decreases in total body fat and waist circumference were observed. The researchers suggest that curcumin's anti-inflammatory and antioxidant properties may underlie these combined benefits, making it a promising adjunctive therapy for managing both liver health and weight.

Disclaimers
This information is for educational purposes only and should not be interpreted as medical advice.
The study discussed was conducted on humans with Type 2 Diabetes and MASLD. Further research may be needed to confirm these findings in other populations.
Always consult with a qualified healthcare professional before making any changes to your diet, supplement regimen, or treatment plan, especially if you have a medical condition or are taking medications.
This channel does not provide medical advice.
#Curcumin #LiverHealth #WeightLoss #MASLD #BMI
Yaikwawong M, Jansarikit L, Jirawatnotai S, Chuengsamarn S. Curcumin for Inflammation Control in Individuals with Type 2 Diabetes Mellitus and Metabolic Dysfunction-Associated Steatotic Liver Disease: A Randomized Controlled Trial. Nutrients. 2025; 17(12):1972. https://doi.org/10.3390/nu17121972
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