U.S. Transhumanist Party Virtual Enlightenment Salon with Matthew “Oki” O’Connor

On Sunday, June 22, 2025, at 1 p.m. U.S. Pacific Time, the U.S. Transhumanist Party invites Dr. Matthew “Oki” O’Connor of Cyclarity Therapeutics to discuss Cyclarity’s efforts to develop new, easy-to-use drugs to prevent atherosclerosis, heart attacks, and strokes by addressing the underlying cause, the build-up of arterial plaque.

The technology of Cyclarity Therapeutics removes arterial plaque by clearing the non-degradable cholesterol that accumulates within cells in the arterial walls. Its products are based on novel derivatives of a well-known, safe compound, and a new way of looking at cardiovascular disease.

Cyclarity's research has combined computational and synthetic chemistry programs to create custom-engineered cyclodextrins (polysaccharides with known industrial and pharmaceutical excipient uses) to capture, and remove from cells, oxidized cholesterol derivatives such as 7-ketocholesterol, which are broadly toxic molecules with no known biological function.

Dr. Matthew O’Connor is the CEO of Scientific Affairs at Cyclarity Therapeutics. He was awarded his Master’s Degree in Neuroscience from Northwestern Medical in 1999 and his Ph.D. in Biochemistry from Baylor College of Medicine in 2005. His postdoctoral research includes work at UC Berkeley on muscle stem cells and aging. He is the former VP of Research at SENS Research Foundation, where he oversaw a broad swath of research projects spanning many aspects of rejuvenation biotechnology from which he authored many papers and patents.

Visit the website of Cyclarity Therapeutics at https://cyclaritytx.com/.