Wall Street to Weed: Hope Wiseman’s Trailblazing Cannabis Journey to Own a Cannabis Dispensary

In this inspiring episode of GO4CEO, we sit down with Hope Wiseman, the groundbreaking entrepreneur behind Mary & Main—the youngest Black woman in the U.S. to own a cannabis dispensary. At just 25, Hope left her role as an equity institutional sales analyst, guided by her economics background and passion for social justice, to launch a venture that would ultimately redefine accessibility and representation in the cannabis industry.

Based in Prince George’s County, Maryland, Mary & Main is more than a dispensary—it’s a community hub that educates customers on medical cannabis, health equity, and the systemic impacts of the War on Drugs. As Hope explains, she’s committed to “killing the stigma” and creating generational wealth for marginalized communities through empowerment and inclusion
CBS News

In this episode, tune in to hear:

How Hope’s finance and economics background fueled her pivot into cannabis

The challenges of entering a federally-illegal industry as a young Black woman, and how she overcame them

The importance of location—Mary & Main reflects Hope’s deep roots in her own community. Mary & Main’s dedication to education, outreach programs, and social equity initiatives that go well beyond retail service.

Whether you’re curious about cannabis entrepreneurship, Black female leadership, or socially conscious startups, this conversation offers practical strategies, bold perspective, and real-world inspiration.

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