clearing_the_smoke_the_science_of_cannabis_2011

Chronic Endocannabinoid Deficiency as the Root Cause of Aging and Death by Natural Causes — A Systems Model Approach as a Means to Reach Longevity Escape Velocity
by Jennifer April Huse ( JAH)

Publication date 2025-08-10
This project presents a systems biology thesis titled "Chronic Endocannabinoid Deficiency as the Root Cause of Aging and Death by Natural Causes — A Systems Model Approach as a Means to Reach Longevity Escape Velocity." It proposes that age-related diseases and death by natural causes are driven by chronic deficiencies in the endocannabinoid system (ECS). The thesis outlines a systems-level model in which ECS deficiency leads to inflammatory signaling dysfunction, neuroendocrine misregulation, organ degradation, and aging. It also explores the therapeutic potential of high-dose cannabinoid saturation to restore ECS balance and both prevent and reverse degenerative conditions.
License Notice
This work is made available under the Creative Commons Attribution–NonCommercial 4.0 International License (CC BY-NC 4.0).
You are free to share and adapt the material for non-commercial purposes only, with attribution.
https://creativecommons.org/licenses/by-nc/4.0/
Source: https://archive.org/details/osf-registrations-64eas-v1