SEED Oils & endothelial inflammation

Seed Oils and Endothelial Inflammation

Seed oils, often extracted from crops such as soybean, corn, sunflower, canola, and safflower, are rich in omega-6 polyunsaturated fatty acids (PUFAs). While small amounts of omega-6 are essential, excessive intake—especially when consumed through refined, industrially processed seed oils—may contribute to oxidative stress and chronic inflammation in the endothelium, the thin inner lining of blood vessels. Research suggests that high levels of omega-6 fatty acids can disrupt the delicate omega-6 to omega-3 ratio, potentially triggering endothelial dysfunction, arterial stiffness, and inflammatory pathways linked to heart disease, atherosclerosis, and metabolic disorders. In contrast, diets balanced with healthier fats—such as omega-3s from fish oil, olive oil, or avocado oil—are associated with reduced vascular inflammation, improved nitric oxide production, and better endothelial health. Understanding the relationship between seed oils and endothelial inflammation is crucial for optimizing cardiovascular health, reducing systemic inflammation, and supporting long-term wellness.

Keywords: seed oils inflammation, endothelial dysfunction, omega-6 fatty acids, vascular health, processed vegetable oils, heart disease risk, arterial inflammation, endothelial lining, oxidative stress, chronic inflammation.

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Endothelial health and vascular disease