Blood Watch

Advanced intravital microscopy techniques, such as multiphoton and light-sheet fluorescence microscopy, enable real-time visualization of blood flow and cellular components within live tissues at submicron resolution.

These systems use near-infrared femtosecond lasers to penetrate deep into vasculature with minimal photodamage, while fluorescent probes tag erythrocytes, leukocytes, and plasma proteins for high-contrast imaging.

Combined with adaptive optics and fast resonant scanning, researchers can track red blood cell velocity, platelet aggregation, and endothelial interactions at frame rates exceeding 60 fps.

Innovations like optical coherence tomography angiography (OCTA) complement this by generating 3D maps of microcirculation without exogenous dyes, allowing dynamic studies of clot formation, immune cell trafficking, and capillary remodeling, essential for cardiovascular research and drug development.