Top Pharmacologist Names the #1 Deadliest Drug to Withdrawal From | Chris McCurdy

Oct 27, 2025
Alcohol withdrawal symptoms can be severe—often harsher than other drugs. Pharmacologist Chris McCurdy explains why and what factors matter.
Why is quitting alcohol so rough for the brain and body?

In this clear, science-backed breakdown, Dr. McCurdy walks through how alcohol changes GABA and glutamate systems, why tolerance builds, and what happens when you suddenly stop. We cover the difference between mild, moderate, and severe withdrawal, why timing (hours vs. days) matters, and how dehydration, sleep loss, and underlying health can make symptoms worse. 🧠

You’ll learn the key signs to watch for (from anxiety and tremors to dangerous complications), how alcohol compares to opioids, stimulants, and nicotine, and why medical supervision is often recommended for heavy or long-term use. We also touch on evidence-based support options and questions to ask a healthcare professional. ⚠️

This episode is for education only and isn’t medical advice. If you or someone you know may be experiencing withdrawal or alcohol-related harm, seek qualified help.

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