Ep 085 - FDA Flips: Menopause & HRT

At last, the FDA has decided to remove the black box warning from topical hormone replacement therapies (HRTs) for menopause after years of pushback from women, and a comprehensive scientific review. We look at the original research that lead to the warnings and present evidence for their removal. Women were suffering unnecessarily because good research was mis-applied, and it took two decades for the government to catch on.

Next, we look at a study showing that nearly half of type 2 diabetes patients exhibit micronutrient deficiencies, with vitamin D being the most prevalent, followed by magnesium and vitamin B12. We discuss how to assess your individual needs and how to supplement effectively.

Finally, heading into Thanksgiving, Josiah helps us refocus and reframe the personality clashes and stress that always come around whenever family gets together.

If you've got a question, we'd love to hear it! Just drop it in the comments or send us an email ([email protected])!

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Generation Health is a podcast discussing cutting edge research and time tested best practices to help you live better, longer. Joey DiMatteo (PharmD, CCN), & Dante DiMatteo (PharmD) are the second generation in a family dedicated to helping educate listeners so they can make informed decisions about their own health. Incorporating their extensive knowledge in pharmaceuticals, nutrition, exercise, and supplementation, they love sharing their wisdom with anyone looking to improve their life!

SHOW NOTES:
1) FDA Removes Warning From Menopause Hormone Therapies (Pharmacy Times) - https://tinyurl.com/mrxxvv69 [Note: Latest Data]
2) Doctors urge FDA to remove outdated warnings (WWL TV) - https://tinyurl.com/yc96uu4e
3) Progesterone for vasomotor symptoms (NIH) - https://tinyurl.com/2htxfwp7
4) Progesterone for treatment of menopausal women (NIH) - https://tinyurl.com/yc6mnu9x
5) Progesterone for perimenopausal night sweats and hot flushes (NIH) - https://tinyurl.com/2e3y3dxv
6) Progesterone may decrease perimenopausal hot flashes, night sweats (Endocrine Society) - https://tinyurl.com/yc4vcbmc
7) Progesterone Therapy for Menopause (Healthline) - https://tinyurl.com/ythxtnt8
8) Micronutrient Deficiencies in Type 2 Diabetes Patients (Pharmacy Times) - https://tinyurl.com/bdfzphks

CHAPTERS:
00:25 - Show Intro
01:12 - HRT Blackbox Article
01:27 - A note from Joey
04:35 - Summary of what's going on
05:23 - Findings from the study
09:35 - When will the warning be removed?
10:51 - Transdermal vs. Oral Estradiol
12:49 - Why would you choose oral over transdermal?
14:52 - Local Estrogen
15:50 - Discussion: Macronutrient Deficiencies with T2D
16:50 - Info about the study
18:24 - Most common deficiencies
20:02 - What are the overlaps
22:45 - What to do with this info?
27:17 - Words of Wisdom: Gratitude & Family
29:15 - Be Anxious about Nothing
32:54 - Trust in the Unseen
36:16 - Changing Your Perspective
48:10 - Takeaway
49:01 - Show outro

DISCLAIMER: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Listeners should NOT disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions.