INSULIN RESISTANCE! MAP TAMING THE SUGAR DRAGON?

3 days ago
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Insulin resistance is a condition where your body's cells become less responsive to insulin, a hormone produced by the pancreas that helps regulate blood sugar levels. When cells are resistant, the pancreas produces more insulin to help glucose enter cells, but over time, this increased effort can wear out pancreatic function, leading to higher blood sugar levels, prediabetes, and eventually type 2 diabetes.​

Causes & Risk Factors
Excess visceral fat around the abdomen and organs

Obesity and physical inactivity

Unhealthy diet — processed foods, refined carbohydrates, and saturated fats

Genetic predisposition or inherited gene variations affecting insulin signaling

Hormonal conditions such as Cushing’s syndrome, acromegaly, and hypothyroidism

Certain medications (steroids, blood pressure drugs, HIV meds)

Chronic stress and lack of exercise​

Symptoms
Early insulin resistance may not cause noticeable symptoms. As it worsens:

Persistent fatigue or low energy

Increased hunger and cravings, especially for sugary foods

Weight gain, especially around the abdomen

Elevated blood glucose levels

Skin tags or darker patches of skin (acanthosis nigricans)

High blood pressure and abnormal cholesterol levels

Diagnosis & Treatment
Diagnosis involves blood tests (fasting glucose, insulin levels, oral glucose tolerance test) along with assessments of waist circumference and other risk factors.
Treatment emphasizes:

Lifestyle modifications: Improve diet, increase physical activity, lose excess weight

Medications: Metformin and other insulin sensitizers may be prescribed

Dietary changes: Reduce intake of sugars, refined carbs, and processed fats

Regular monitoring and managing associated conditions like high blood pressure and cholesterol

Managing Insulin Resistance
Lifestyle changes, especially weight loss and exercise, significantly improve insulin sensitivity and overall health. Early management prevents progression to type 2 diabetes and reduces cardiovascular risk.

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