SLU-PP-332: What Changed After a Year (And Why We Were Wrong)

[00:00] Introduction & The New Understanding of SLU
[04:59] SLU: The Pan ERR Agonist & Key Genes (DDIT4, SLC)
[13:58] SLU's Mechanism: Reprogramming Metabolism
[19:04] Redox State: The Tide Analogy & Why It Matters
[25:20] The Cholesterol Factor in SLU Response
[28:47] Oral Dosing Strategy & Avoiding Overload/Excessive Uncoupling
[42:07] Oral vs. Injectable: Bioavailability & Safety
[49:49] Metrics to Evaluate SLU's Success (RER, HRV, etc.)
[54:08] Drug Interactions (Polypharmacy) & Who Should Avoid SLU
[01:04:48] Summary & Redux is Everything