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TMG Isn’t for Everyone — Here’s Why
Most people think supplements either “work” or “don’t work.”
But when it comes to TMG (trimethylglycine), the truth is far more complex.
Some people feel clear, calm, energized, and focused…
Others feel anxious, wired, overstimulated, or worse.
So what’s actually going on?
In this video, Pharmacist Michael explains:
✅ Why TMG helps some people and backfires for others
✅ How methylation really works (and why more isn’t always better)
✅ The signs your body is overmethylating
✅ Why TMG can increase anxiety in certain people
✅ How to use TMG safely — or know when to stop
🧠 What You’ll Learn in This Video:
What methylation actually does in the body
Why TMG boosts energy and mood for some people
Why others feel anxious, wired, or overstimulated
How dopamine, norepinephrine, and SAMe are involved
The difference between under-methylation and over-methylation
How to tell if TMG is right for your biology
Safe dosing strategies and common mistakes
How to calm an overstimulated nervous system
⏱️ Timestamps:
00:00 Why TMG feels amazing for some (and terrible for others)
00:35 The Part No One Talks About
01:14 Who Tends to Feel Great on TMG
03:31 Why Some People Feel Terrible on TMG
06:16 The Methylation Balance Concept
06:50 Signs You May Need to Go Slow
08:57 How to use TMG Safely
11:14 Final Thoughts
⚠️ Important Note:
TMG is a powerful methyl donor — not a casual supplement.
If you’re sensitive to caffeine, have anxiety, or take other methylated nutrients, this video is especially important for you.
👨⚕️ About This Channel:
I’m Pharmacist Michael — a board-certified clinical pharmacist specializing in mental health and integrative medicine.
My goal is to help you understand how medications and supplements actually work, without hype or fear.
👍 If this helped, give it a like
🔔 Subscribe for honest, science-based health content
💬 Comment below: Did TMG help you — or make things worse?
🔍 Related Videos You Might Like:
• Best Supplements for Anxiety (That Actually Work)
• Why Some Supplements Make Anxiety Worse
• Methylation Explained Simply
• TMG vs SAMe – What’s the Difference?
Informed patients make better decisions.
Be happy. Be healthy.
Don’t forget to visit our website https://pharmacistmichael.com
My new course on Treating Anxiety Without Medications is now available on Udemy:
https://www.udemy.com/course/fighting-anxiety-without-medication/
To learn more about Pharmacist Michael and the products he recommends, check out his beacons link below
https://beacons.ai/pharmacist_michael
Click my Amazon Store link below where you can find products I use to create my videos and other items I use in my daily life:
https://www.amazon.com/shop/influencer-00f9a2a8?ref=ac_inf_hm_vp
Supplements I use:
👉 Ashwagandha: https://amzn.to/4kXiD4N
👉 Tongkat Ali: https://amzn.to/4nic9iy
👉 Zinc (Picolinate or Chelated): https://amzn.to/4kbq3QO
👉 Vitamin D3: https://amzn.to/3IeOVtz
👉 Magnesium Glycinate: https://amzn.to/44zvmoA
👉 Boron: https://amzn.to/4eiyBUI
🛒 TMG (Trimethylglycine): https://amzn.to/45a9b7z
🛒 Glycine Capsules: https://amzn.to/45eWmcm
🛒 Homocysteine Testing Kit: https://amzn.to/4olLHW4
THORNE - Vitamin B12 - as Methylcobalamin: https://amzn.to/4of20DS
→ L-Tyrosine: https://amzn.to/3Hgsrsb
→ Rhodiola Rosea: https://amzn.to/479CLwA
→ Vitamin C: https://amzn.to/450nMni
Alpha-GPC: https://amzn.to/41vnd2D
CDP-choline (citicoline): https://amzn.to/45kBCQf
Omega-3s: https://amzn.to/474H1h9
ALCAR – https://amzn.to/45rEhaS
Below are links to companies I believe can help you be happy and healthy:
LYFEfuel
https://www.awin1.com/awclick.php?gid=447117&mid=35059&awinaffid=1340171&linkid=3411301&clickref=
Firecracker Farms Spicy Salt:
https://shop.firecracker.farm/discount/PHARMACISTMICHAEL?ref=MICHAELBROWN
Vita Living:
https://www.awin1.com/awclick.php?gid=521540&mid=63886&awinaffid=1340171&linkid=4010893&clickref="
Buy me a coffee:
https://www.buymeacoffee.com/pharmacist_michael
This description section may contain links to affiliate websites, and we receive an affiliate commission for any purchase made by you on the affiliate website using such links. Our affiliates include Awin (Affiliate Window) and ShareASale. We are a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for us to earn advertising fees by linking to Amazon.com and affiliated websites.
This video cannot and does not contain medical/health advice. The medical/health information is provided for general informational and educational purposes only and is not a substitute for professional advice. Accordingly, before taking any actions based upon such information, we encourage you to consult with the appropriate professionals. We do not provide any kind of medical health advice. THE USE OR RELIANCE OF ANY INFORMATION CONTAINED IN THIS VIDEO IS SOLELY AT YOUR OWN RISK.
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