AMD MI60 ComfyUI: LTX-2 Image-to-Video Workflow Guide

In this screencast, we are focusing on a high-performance Image-to-Video (I2V) workflow using the LTX-2 model on the AMD Instinct MI60. You will learn how to reinstall ComfyUI and ROCm 6.4 to properly support this hardware for generative AI tasks. We will demonstrate how to use LTX-2 GGUF weights combined with the Gemma-3-12B-it instruction-tuned model for superior prompt adherence. We also show how to implement camera control using the Dolly Left LoRA to add professional cinematic motion to your AI-generated videos. This tutorial is designed to be beginner-friendly and clear for those setting up AI on AMD GPUs.

Read the related blog articles:
https://ojambo.com/reinstall-comfyui-and-rocm-6-4-for-unsupported-amd-instinct-mi60-gpu

https://ojambo.com/review-generative-ai-wan-2-2-t2v-14b-model

Model Weight Links:
LTX-2 GGUF: https://huggingface.co/vantagewithai/LTX-2-GGUF

Camera Control Dolly Left LoRA: https://huggingface.co/Lightricks/LTX-2-19b-LoRA-Camera-Control-Dolly-Left

Gemma-3-12B-it GGUF: https://huggingface.co/nocturne23/gemma-3-12b-it-Q4_K_M-GGUF

Base LTX-2: https://huggingface.co/Lightricks/LTX-2

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