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【68】ウイルスの増殖速度から伝搬力と病害性を予測する - 大橋眞
ウイルス性気道感染症の症状や他の人への伝搬力は、およそ気道上皮細胞で産生されるウイルス量に比例すると考えられます。インフルエンザウイルスと新型コロナウイルスと増殖速度は、どの程度違いがあるのでしょうか。培養細胞による増殖速度から、両者を比較してみます。厳密には、細菌のような2分裂で増殖しないので、倍化時間のような概念は使えないのですが、およその増加速度を比較することは可能です。
新型コロナの培養に関する2つの論文のデータとの培養による増殖を比較しました。その結果、新型コロナウイルスの増殖速度は、インフルエンザウイルスと比較して、計算上は1万分の1以下になりました。その結果、新型コロナウイルスの増殖は、大変緩やかであり、ほとんど他への伝搬力を持たず、症状を起こすような増殖をしないウイルスであり、個体数としてもマイナーな常在ウイルスと考えられました。
Symptoms of viral respiratory tract infections and their ability to propagate to others are thought to be approximately proportional to the amount of virus produced by airway epithelial cells. How different is the growth rate between influenza virus and the new coronavirus? Let's compare the two based on the growth rate of the cultured cells. Strictly speaking, it does not grow in two divisions like bacteria, so it is not possible to use concepts such as doubling time, but it is possible to compare the approximate rate of increase.
We compared the growth by culture with the data of two papers on the culture of the new corona. As a result, the growth rate of the new coronavirus is calculated to be less than 1 / 10,000 of that of the influenza virus. As a result, the growth of the new coronavirus is very slow, it has almost no transmission power to others, it does not grow to cause symptoms, and it is considered to be a minor resident virus in terms of population. It was.
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