FDA Fast Track Application for Tempol - A Potential At Home COVID Therapy

FDA Fast Track Application for Tempol - A Potential At Home COVID Therapy

Recently, researchers from the National Institutes of Health (NIH) highlighted Tempol as a potential home antiviral treatment for COVID-19 (https://covid19.nih.gov/news-and-stories/tempol-potential-home-treatment-covid-19). Let's review the mechanism of this drug.

URL list from Wednesday, Jan. 26 2022

Adamis Pharmaceuticals Announces a Publication with the Human Immune Monitoring Center at Stanford Demonstrating Tempol Significantly Inhibited Multiple Cytokines from COVID-19 Patient’s Cells | Adamis Pharmaceuticals Corporation
https://ir.adamispharmaceuticals.com/news-releases/news-release-details/adamis-pharmaceuticals-announces-publication-human-immune

TEMPOL: A Potential Home Treatment for COVID-19 | NIH COVID-19 Research
https://covid19.nih.gov/news-and-stories/tempol-potential-home-treatment-covid-19

Brief report: Tempol, a novel antioxidant, inhibits both activated T cell and antigen presenting cell derived cytokines in-vitro from COVID-19 patients - PMC
https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC8378988/

Study to Evaluate the Effects of Tempol (MBM-02) in COVID-19 Patients. - Full Text View - ClinicalTrials.gov
https://clinicaltrials.gov/ct2/show/NCT04729595

Peripheral blood mononuclear cell - Wikipedia
https://en.wikipedia.org/wiki/Peripheral_blood_mononuclear_cell#:~:text=A%20peripheral%20blood%20mononuclear%20cell,)%20have%20multi%2Dlobed%20nuclei.

Interleukin 1 beta - Wikipedia
https://en.wikipedia.org/wiki/Interleukin_1_beta

Granulocyte-macrophage colony-stimulating factor - Wikipedia
https://en.wikipedia.org/wiki/Granulocyte-macrophage_colony-stimulating_factor

CCL20 - Wikipedia
https://en.wikipedia.org/wiki/CCL20

Interleukin 10 - Wikipedia
https://en.wikipedia.org/wiki/Interleukin_10

Interleukin 2 - Wikipedia
https://en.wikipedia.org/wiki/Interleukin_2#:~:text=Interleukin%2D2%20(IL%2D2,that%20are%20responsible%20for%20immunity.

Interleukin 6 - Wikipedia
https://en.wikipedia.org/wiki/Interleukin_6

Interleukin 21 - Wikipedia
https://en.wikipedia.org/wiki/Interleukin_21