Relationship between muscle mass and energy expenditure.

Understanding that the balance between energy intake and expenditure is regulated through signals that connect the central nervous system to the rest of the body, and that each endocrine gland is directly associated with an energy center. Daily energy requirements (DER) encompass resting energy expenditure (REE), physical activity, the thermogenic effect of food, and growth. REE represents basal metabolic rate (BM) plus the energy required to maintain awake activity while muscularly resting. * The Schofield equation refers to a series of equations developed by Dr. William Schofield in the mid-20th century to estimate Basal Metabolic Rate (BMR) and Total Energy Expenditure (TEE) in adults. These equations were based on a large dataset of metabolic rate measurements from various populations.